The Flame Angelfish requires at least a 70-gallon aquarium with lots of hiding places and live rock for grazing. The Flame Angelfish can be prone to nip at stony and soft corals, and clam mantles. If the Flame Angelfish is to be added to a peaceful community, it should be the last fish introduced. The Flame Angelfish adapts well to aquarium life, but should be kept in an established system and housed with dissimilar genera. The Flame Angel is very sensitive to elevated levels of copper, and should never be exposed to levels near or above 0.15 ppm.
The Flame Angelfish is hermaphroditic, very difficult to breed in an aquarium, and has no distinguishable differences in color between male to female.
The diet of the Flame Angelfish should consist of Spirulina, marine algae, high-quality angelfish preparations, mysis or frozen shrimp, and other high-quality meaty items.